Laboratory of
Shanna Hamilton
Our overarching goal is to decipher molecular mechanisms of calcium regulation in the healthy and diseased heart, with the end goal of uncovering novel therapeutic strategies to treat arrhythmias and heart disease.
To study these pathways, my laboratory uses a comprehensive experimental approach from molecule-cell-organ-organism. We use mouse and rat models of both inherited (catecholaminergic polymorphic ventricular tachycardia, long QT syndrome) and acquired (hypertrophy, heart failure, aging, diabetes, atrial fibrillation) cardiac disease. Methods we use include molecular biology, high-resolution confocal microscopy and live cell imaging, electrophysiology, whole heart optical mapping and in vivo gene editing.
Lab Members
Lab Staff
For further information, contact Shanna Hamilton, PhD at 520-626-6867 or
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