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Rachel Sadler

Graduate Student
Rachel Sadler

PO Box 245241
Building: Medical Research Building (#241)
Room #: 330E

rlsadler@arizona.edu

I am interested in the functional and structural roles of cardiac myosin binding protein-C (cMyBP-C). My projects include 1. investigating the consequences of missense mutations in cMyBP-C's N-terminal region that alter its affinity for thin filaments and 2. uncovering mechanisms which cMyBP-C haploinsufficiency (reduced protein levels) causes hypertrophic cardiomyopathy.